Precision Medicine

Much of medicine today is based on large-scale trials and the average responses of thousands of people.

But we are entering a future in which medicine will be personalized--a future in which your particular variety of disease can be identified at the molecular level, even from information contained in a single cell, and then you can be given the treatment with the best chance for success for you, with the least side effects.

Less trial-and-error, more precision.

AD&T's Precision Medicine Program

The practice of precision medicine is emerging quickly, particularly in oncology, but there is still a long way to go to apply it broadly across healthcare. There are many difficult scientific questions still to be asked and answered, and there are many challenges in turning a discovery in the lab into a tested and widely accepted tool for doctors.

In Notre Dame's Advanced Diagnostics & Therapeutics initiative, new discoveries in precision medicine are made through a rapidly growing program in which analytical scientists and bioengineers collaborate directly with physicians, health systems, and healthcare companies to find solutions to widespread high-mortality and high-cost diseases and conditions.

More background:


  • Cleveland Clinic Innovations

  • The Feinstein Institute for Medical Research

  • Harper Cancer Research Institute

  • Icensa - Interdisciplinary Center for Network Science and Applications

  • Indiana University School of Medicine-South Bend

  • Marshfield Clinic

  • Memorial Hospital of South Bend

  • Naval Medical Research Center

  • Saint Joseph Regional Medical Center

  • SAP

  • FIU

  • EnDx

  • OndaVia

  • UPennMed


Through our partners, both internal and external, we are focusing our research on a growing list of urgent medical problems, including cancer, infectious diseases, severe inflammatory conditions, chronic wound healing, and congenital birth defects.

Within these broad categories, we are working on such efforts as:

  • improved diagnostics and treatments for sepsis, the leading cause of death from infection in the world and the costliest condition for U.S. hospitals
  • a better diagnostic and prognostic tool that takes into account the genetic differences in colon cancers
  • a new field-deployable biochip platform for tracking viruses and biowarfare agents
  • cutting-edge treatments for diabetic wound healing
  • biotechnologies the reduce resistance to chemotherapeutics for multiple myeloma and breast cancer

Program Leaders


 Norm Dovichi

Grace Rupley Professor of Chemistry and Biochemistry


Paul Bohn

Schmitt Professor of Chemical and Biomolecular Engineering

Professor of Chemistry and Biochemistry


For more information about AD&T's Precision Medicine program, please contact:

Arnie Phifer
Advanced Diagnostics & Therapeutics

Twitter: @NDprecisionmed