Much of medicine today is based on large-scale trials and the average responses of thousands of people.
But we are entering a future in which medicine will be personalized--a future in which your particular variety of disease can be identified at the molecular level, even from information contained in a single cell, and then you can be given the treatment with the best chance for success for you, with the least side effects.
Less trial-and-error, more precision.
AD&T's Precision Medicine Program
The practice of precision medicine is emerging quickly, particularly in oncology, but there is still a long way to go to apply it broadly across healthcare. There are many difficult scientific questions still to be asked and answered, and there are many challenges in turning a discovery in the lab into a tested and widely accepted tool for doctors.
In Notre Dame's Advanced Diagnostics & Therapeutics initiative, new discoveries in precision medicine are made through a rapidly growing program in which analytical scientists and bioengineers collaborate directly with physicians, health systems, and healthcare companies to find solutions to widespread high-mortality and high-cost diseases and conditions.
Through our partners, both internal and external, we are focusing our research on a growing list of urgent medical problems, including cancer, infectious diseases, severe inflammatory conditions, chronic wound healing, and congenital birth defects.
Within these broad categories, we are working on such efforts as:
- improved diagnostics and treatments for sepsis, the leading cause of death from infection in the world and the costliest condition for U.S. hospitals
- a better diagnostic and prognostic tool that takes into account the genetic differences in colon cancers
- a new field-deployable biochip platform for tracking viruses and biowarfare agents
- cutting-edge treatments for diabetic wound healing
- biotechnologies the reduce resistance to chemotherapeutics for multiple myeloma and breast cancer
Grace Rupley Professor of Chemistry and Biochemistry
Schmitt Professor of Chemical and Biomolecular Engineering
Professor of Chemistry and Biochemistry